Gloucester Rugby are in search for qualification to the knock-out stages of the Anglo-Welsh Cup, which will be their second in as many weeks.
Johan Ackermann’s side host an in-form Ospreys on Friday evening before travelling to Newcastle Falcons in a fortnight.
The Cherry and White’s narrowly lost to Leicester Tigers 26-24 in their opening game but responded well as they ran away with a 47-7 win over London Irish.
The West Country based club qualified for an away quarter-final berth in the European Challenge Cup against Irish side Connacht Rugby despite a 34-24 defeat at Kingsholm, their first defeat at home of the season.
With a rich history of late in the European competition, having reached the final last season and winning the competition the year before that, Gloucester are accustomed to knock-out rugby.
Ackermann will look to play a mixture of youth and experience in a bid to not only qualify for the next stage of the competition but to rest key players in order to maintain their push in the Aviva Premiership.
Ospreys are in a similar position to Gloucester and will require a win from this game, having four points from two games with their only win a 26-16 victory coming over Welsh rivals Cardiff Blues.
The Swansea based club opened up there campaign with a heavy defeat at Liberty Stadium to Wasps in a 12-36 romp.
Since their previous Anglo-Welsh Cup appearances Ospreys have had an upturn in fortune both in the Pro 14 and European Champions Cup, despite not qualifying for the quarter-finals.
Another side that stand in the wake of Gloucester Rugby are Newcastle Falcons, a side rich in form in the Aviva Premiership and the north-east club are the only team in the competition to have scored over 100 points in their first two games.
Topping their group with ten points following two bonus-point wins, Falcons are currently the strongest candidates in the competition being one of only three sides to pick up all points on offer.